Dar-Fu Tai

Professor,  Bioorganic Chemistry

 Phone

Office：(03)-890-3579

Lab    ：(03)-890-3580

 Office

D313  Science building 

  Laboratory

D314、D315 Science building 

  e-mail

 dftai@gms.ndhu.edu.tw

  Personal Website

 Education 

Ph.D., University of Pittsburg 1985 　

  Experience

Postdoctoral Fellow at Department of Chemistry, Massachusetts Institute of Technology 1985-1986,

Postdoctoral Fellow at Department of Applied Biological Science, Massachusetts Institute of Technology 1987,

Associate Research Fellow at Division of Biochemistry, Development Center for Biotechnology 1988-1990,

Associate Professor at Department of Food Engineering, Da-Yeh University 1990-1995,

Professor at Department of Food Engineering, Da-Yeh University 1996,

Professor at National Dong-Hwa University 1996-present

 

 

1)Development of Artificial Enzymes.

2)Surface Imprinting of Artificial Receptor on Chips for the Detection of Virus, Proteins,  

   Peptides, and Small Molecules.

3)Asymmetric Synthesis Using Molecular Imprinted Polymer as the Auxiliary.

4)Understanding the Molecular Mechanisms Underlying the Formation of Supermolecules

   between Taste Receptor and Artificial Sweeteners.

5)Peptide Related Drug Design and Synthesis.

6)Discrimination of Human Plasma Proteins for Proteomic Research.

 

 

 

  Selected Publications

1. Dar-Fu Tai,* Chung-Yin Lin, Tzong-Zeng, Jyh-Hsiung Huang and Pei-Yun Shu (2006) “Artificial receptors in serologic tests for the early diagnosis of dengue virus infection” Clin. Chem. 52, 1486-1491. SCI

2. Kuo-Haw Lu, Dar-Fu Tai* (2006). “Diagnostic aspects of human plasma proteins” Chemistry (in Chinese), 64, 119-128.

3. Chi-Tai Chen and Dar-Fu Tai* (2006). "Sweeteners, sweet proteins and their taste receptor" Chemistry (in Chinese), 64, 129-140.

4. Dar-Fu Tai* and Ai-Xuan Yeh (2006). "Enzymic synthesis of D-amino acids and their oligomers " Chemistry (in Chinese), 64, 377-386.

5. Dar-Fu Tai*, and Y. F. Lin (2008) “Molecularly Imprinted Cavities Template the Macrocyclization of Tetrapeptides” Chem. Commun., 2008, 5598-5600. SCI

6. Yee-Fung Lin, Shih-Ming Lee, Chi-Tai Chen, Kuo-Hau Lu, Dar-Fu Tai, (2009) “On-surface cyclization of tetrapeptides using molecularly imprinted polymers as non-covalent auxiliaries” J. Chin. Chem. Soc. 56, 127-134. SCI

7. Dar-Fu Tai*, Ming-Hong Jhang, Guan-Yu Chen, Sue-Chen Wang, Kuo-Hao Lu, Yu-Der Lee, and Hsin-Tzu Liu (2010) “Epitope-cavities generated by Molecularly Imprinted Films Measure the Coincident Response to Anthrax Protective Antigen and Its Segments” Anal. Chem. 82, 2290–2293. SCI

8. Dar-Fu Tai,*, Yi-Fang Ho, Cheng-Hsin,Wu, Tzu-Chieh Lin, Kuo-Hao Lu, Kun-Shian Lin (2011) “Artificial-Epitope Mapping for CK-MB Assay” Analyst, 136, 2230 - 2233.

9. Horng-Jyh Harn, Shinn-Zong Lin, Po-Cheng Lin, Cyong-Yue Liu, SY Yen, Li-Fu Chang, Po-Yen Liu, Dean-Kuo Hsieh, Fu-Chen Liu, Dar-Fu Tai, Tzyy-Wen Chiou “Local interstitial delivery of z-butylidenephthalide by polymer wafers against malignant human gliomas” Neuro-Oncology, 2011 doi:10.1093/neuonc/nor021.