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Yen-Peng Ho

Professor,  Analytical Chemistry

 

 

 

  Phone    

Office:(03)-890-3591

Lab   :(03)-890-3592

   Office

A207 Science building 3

   Laboratory

A301/A303 Science building 3

   e-mail ypho@gms.ndhu.edu.tw

 

    Personal Website

 http://faculty.ndhu.edu.tw/~yphoweb/HoHomePage.htm

  Education
1991-1996: Ph. D. PhysicalChemistry, Case Western Reserve Univ. Cleveland, OH, USA
1982-1986: Bachelor degree of National Chung-Hsing University, Taichung, Taiwan
 

    Experience

National Dong-Hwa University, department of chemistry, Professor 2007-
National Dong-Hwa University, department of chemistry, Associate Professor 2003-2007
National Dong-Hwa University, department of chemistry, Assistant Professor 1999-2003
University of Maryland, Maryland, USA, Research Associate 1997-1999
Colorado School of Mines, Golden, CO,USA, Research Associate 1996-1997

     Research Interests

Mass spectrometry
 
Bioanalytical Chemistry
 

     Selected Publications

 

1. Chen, C.-T.; Reddy, M.; Ma, Y.-R.; Ho, Y.-P. * “Mass spectrometric identification of pathogens in foods using a zirconium hydroxide immobilization approach”International J. Mass Spectrom. 2012. (In press)

2. Ho, Y.-P.* and Reddy, M. “Advances in Analysis of Pathogens by Mass Spectrometry” Mass Spectrom. Rev. 2011,  30, 1203-1224.

3. Ho, Y.-P.; Kuo, C.-W.; Hsu, Y.-T.; Huang, Y.-S.; Yew, L.-P.; Huang, W.-F.; Lin,K.-C.; Hsu, J.-H.* ” β-Actin is a downstream effector of the PI3K/AKT signaling pathway in myeloma cells” Mol. Cellular Biochem. 2011, 348, 129-139.

4. Chen, C.-T. Wang, L.-Y.; Ho, Y.-P.* “Highly Specific Enrichment of Phosphopeptides with Polyethylenimine-Modified Magnetic Nanoparticles for Mass Spectrometric Analysis”Anal. Bioanal. Chem. 2011, 399, 2795-2806.

5.Yang, S.-H.; Reddy, M.; Ho, Y.-P.* “Concentration and In-situ Detection of Peptides Using Liquid MALDI Matrices”Anal. Chem. 2010, 82, 44-48.

6. Reddy, M.; Hsu, W.I.; Hu, J.-F.; Ho, Y.-P.* “Digestion Completeness of Microwave-Assisted and Conventional Trypsin-Catalyzed Reactions” J. Amer. Soc.Mass Spec. 2010, 21, 421-424.

7. Ho, Y.-P.*; Reddy, M. “Identification of Pathogens Using Mass Spectrometry” Clinical Chem. 2010, 56, 525-536.

8. Ho, Y.-P.*; Reddy, M. “Identification of Pathogens Using Mass Spectrometry” Clinical Chem. 2010, 56, 525-536.

9. Li, Y.-Z.; Ho, Y.-P.; Chen, S.-T.; Shiuan, D.* “Proteomic Analysis of the Interactions between Mycoplasma hyopneumoniae and Porcine Tracheal Ciliated Cells” 2010, 160, 2248-2255.

10. Ho, C.-H.; Chen, L.; Ho Y.-P.; Yang, C.-L.* “Oxidative Decomposition of Reactive Blue CI 19 with Sodium Hypochlorite” Environ. Eng. Sci. 2010, 27, 101-109.

11. Li, Y.-Z.; Ho, Y.-P.; Chen, S.-T.; Chiou, T.-W.; Li, Z.-S.; Shiuan, D. “Proteomic comparative analysis of pathogenic strain 232 and avirulent strain J of Mycoplasma hyopneumoniae” Biochemsitry-Moscow 2009, 74 , 215-220.

12. Ho, Y.-P.* and Reddy, M. “Mass spectrometry-based approaches for the detection of proteins of  taphylococcus species” Infectious Disorders-Drug Targets 2008, 8, 166-182.

13. Reddy, p. M.; Ho, Y.-P.*; Shanker K.; Rohini, R.; Ravinder, V.* “Physicochemical and biological characterization of novel macrocycles derived from o-phthalaldehyde” European Journal of Medicinal Chemistry 2009, 44, 2621-2625.2

14. Rohini, R.; Shanker, K.; Reddy, P. M.; Ho, Y.-P*.; Ravinder, V., Mono and is-6-arylbenzimidazo[1,2-c]quinazolines: A new class of antimicrobial agents. European Journal of Medicinal Chemistry 2009, 44, 3330–3339.

15. Shanker K.; Rohini, R.; Ravinder, V.*; Reddy, P. M.; Ho, Y.-P.* “Ru(II) complexes of N4 and N2O2 macrocyclic Schiff base ligands: Their antibacterial and antifungal studies” Spectrochimica Acta Part A 2009, 73, 205–211.

16. Ho, Y.-P.* ; Reddy, M.; Chen, C.-T. and Lo, A. A.-L. “Applications of mass spectrometry in microbial forensics” Forensic Science Review 2009, 21, 25-50.

17. Sun, M.-C.; Chen, C.-D.; Huang, Y.-S.; Wu, Z-S. and Ho, Y.-P.* “Matrix Assisted Laser Desorption/Ionization-MS-Based Relative Quantification of Peptides and Proteins using Iodoacetamide and N-ethyliodoacetamide as Labeling Reagents” J. Sep. Sci. 2008, 31, 538-547.

18. Chang, C.-C.;Chen, P.-H.; Chu, H.-L.; Lee, T.-C.; Chou, C.-C.; Chao, J.-I.; Su, C.-Y.; Chen, J.-S., J.-S.; Tsai, C.-M.; Ho, Y.-P.; Sun, K.-W.; Cheng, C.-W.; Chen, F.-R. “Laser induced popcornlike conformational transition of nanodiamond as a nanoknife” Appl. Phys Lett. 2008, 93, 033905.

19. Liu, K.-K.; Chen, M.-F.; Chen, P.-Y.; Lee, T.; Cheng, C.-L.; Chang, C.-C.; Ho, Y.-P.; Chao, J.-I. “Alpha-bungarotoxin binding to target cell in a developing visual system by carboxylated nanodiamond” Nanotechnology, 2008, 19, 205102.

20. Hu, A.; Lo, A. A.-L.; Chen, C.-T.; Lin, K.-C.; Ho, Y.-P.* “Identifying Bacterial Species using Electrophoresis–Mass Spectrometry and SEQUEST with an Empirical Scoring Function” Electrophoresis. 2007, 28, 1387-1392.

21. Yang, M.-W.; Chen, L.-T.; Yang, Y.-C.*; Ho, Y.-P.* “Determining the Relative Bond Dissociation Energies of the Sodium Salts of Amino Acids by Mass Spectrometry and the Kinetic Method” J. Mass Spectrom. 2007, 42, 542-544.

22. Ho, Y.-P.; Yang, M.-W.; Chen, L.-T.; Yang, Y.-C.* “Relative Calcium Binding Strengths of Amino Acids Determined Using the Kinetic Method” Rapid Commun. Mass Spectrom. 2007, 21, 1083-1089.

23. Chang, C.-C.; Chao, J.-I.; Ho, Y.-P. ; Sun, K.-W.; Cheng, C.-L. “Nano-manipulation on cancer cells by protein-nanodiamond complex” Biophys. J. 2007, 332A-332A Suppl. S

24. Hu, A.; Chen, C.-T.;Tsai, P.-J.; Ho, Y.-P.* “Using Capillary Electrophoresis–Selective Tandem Mass Spectrometry to Identify Pathogens in Clinical Samples” Anal. Chem. 2006, 78, 5124-5133.

25. Lo, A. A.-L.; Hu, A.; Ho, Y.-P.* “Identification of Microbial Mixtures by LC-Selective Proteotypic-peptide Analysis (SPA)” J. Mass Spectrom. 2006, 41, 1049-1060.

26. Hu, A.; Tsai, P.-J.; Ho, Y.-P.* “Identification of Microbial Mixtures by Capillary Electrophoresis/Selective Tandem Mass Spectrometry” Anal. Chem. 2005, 77, 1488-1495. 3

27. Lin, S.-S.; Wu, C.-H.; Sun, M.-C.; Sun, C.-M.; Ho, Y.-P.* Microwave-Assisted Enzyme-Catalyzed Reactions in Various Solvent Systems J. Am. Soc. Mass Spectrom. 2005, 16, 581-588.

28. Chang, C.-C.; Lin, P.-Y.; Yeh, X.-C.; Deng, K.-H.; Ho, Y.-P.; Kan L.-S. Protein folding stabilizing time measurement: A direct folding process and three-dimensional random walk simulation Biochem. Biophys. Research Commun.2005, 328, 845–850. 

 Patent

1.  Use of Matrices Comprising Liquids and Light Absorbing Particles for Analysis of Microorganisms by Laser Desorption Mass Spectrometry USA5948610