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Jia -Liang Zhu


 Organic Chemistry








Lab    :(03)-890-3584


D308 Science building


D305、D306 Science building



  Personal Website


Ph. D., University of Alberta (1999) 



Postdoctoral Fellow, University of Calgary (1999-2000);
National Tsing Hua University (2000-02)
Associated Investigator, Taigen Biotechnology (2002-05)
Assistant Professor, Department of Chemistry, National Dong Hwa University (2005-2009)
Associate Professor, Department of Chemistry, National Dong Hwa University (2009-)
Professor, Department of Chemistry, National Dong Hwa University (2015-)


  Research Interests



We are involved in research in two major areas of organic synthesis: 1) development of new synthetic methods and application of these methods into total synthesis of natural products, 2) design and synthesis of biologically active compounds as potential drug candidates.

  Selected Publications

  1. Jia-Liang Zhu*, Sih-Ting Wu and Jr-Yun Shie “Access to Functionalized
    Bicyclo[4,3,0]nonenes via Palladium-Catalyzed Oxidative Cyclization of 2-
    Allylcyclohexyl Oximes” J. Org. Chem. 2014, 79, 3623-3633 (SCI)
  2. Jr-Yun Shie and Jia-Liang Zhu* “Synthesis of Bicyclic γ-Butyrolactone
    Derivatives by Rhodium Catalyzed Intramolecular C-H Insertion of α-Dizao α-
    Phosphoryl Cycloalkyl Esters” Tetrahedron 2016, 72, 1590-1601 (SCI)
  3. Yi-Jung Chiang and Jia-Liang Zhu* “UV-mediated decomposition of
    diazomalonates in benzene: Unexpected access to functionalized
    bicyclo[3.2.0]heptane skeleton” Tetrahedron Lett. 2017, 58, 3081-3084 (SCI)
  4. Jia-Liang Zhu * and Yung-Peng Wu “Rhodium-Catalyzed Intramolecular
    Cyclopropanation of α-Diazo-β-ketonitriles Containing Unsaturated-Substituted
    Cycloalkyl Groups” Synlett 2017, 28, 1467-1472 (SCI)
  5. Kuo-Hsin Chen, Yi-Jung Chiang and Jia-Liang Zhu* “Rhodium-catalyzed
    cyclization of acceptor-substituted biphenyl α-diazoketones: a study of the
    substitution effect on chemoselectivity” Org. Biomol. Chem. 2018, 16, 8353-
    8364 (SCI)
  6. Jia-Liang Zhu* and Yi-Ting Tsai “Rhodium-Catalyzed Aerobic Decomposition
    of 1,3‐Diaryl‐2‐diazo‐1,3‐diketones: Mechanistic Investigation and
    Application to the Synthesis of Benzils” J. Org. Chem. 2021, 86, 813-828 (SCI)
  7. Yi-Ting Tsai and Jia-Liang Zhu* “Rhodium-Catalyzed Aerobic Conversion of 2-
    Diazo-1,3-dicarbonyls to Vicinal Tricarbonyl Compounds and Their In-Situ
    Stability Toward Oxidative Degradation” J. Mol. Struct. 2023, vol. 1274 (part 2),
    134521 (SCI)